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Modulation of Rho Guanine Exchange Factor Lfc Activity by Protein Kinase A-Mediated Phosphorylation

Lfc is a guanine nucleotide exchange factor (GEF) for Rho that demonstrates an unusual ability to associate with microtubules. While several phosphorylated residues have been detected in the Lfc polypeptide, the mechanism(s) by which phosphorylation regulates the exchange activity of Lfc remains unc...

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Detalhes bibliográficos
Main Authors: Meiri, David, Greeve, Melissa A., Brunet, Andrea, Finan, Dina, Wells, Clark D., LaRose, Jose, Rottapel, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772734/
https://ncbi.nlm.nih.gov/pubmed/19667072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01268-08
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