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Meiotic DNA Double-Strand Break Repair Requires Two Nucleases, MRN and Ctp1, To Produce a Single Size Class of Rec12 (Spo11)-Oligonucleotide Complexes
Programmed DNA double-strand breaks (DSBs) in meiosis are formed by Spo11 (Rec12 in fission yeast), a topoisomerase II-like protein, which becomes covalently attached to DNA 5′ ends. For DSB repair through homologous recombination, the protein must be removed from these DNA ends. We show here that R...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772569/ https://ncbi.nlm.nih.gov/pubmed/19752195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01127-09 |
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