Ctp1(CtIP) and Rad32(Mre11) Nuclease Activity Are Required for Rec12(Spo11) Removal, but Rec12(Spo11) Removal Is Dispensable for Other MRN-Dependent Meiotic Functions

The evolutionarily conserved Mre11/Rad50/Nbs1 (MRN) complex is involved in various aspects of meiosis. Whereas available evidence suggests that the Mre11 nuclease activity might be responsible for Spo11 removal in Saccharomyces cerevisiae, this has not been confirmed experimentally. This study demon...

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Hlavní autoři: Hartsuiker, Edgar, Mizuno, Kenichi, Molnar, Monika, Kohli, Juerg, Ohta, Kunihiro, Carr, Antony M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655602/
https://ncbi.nlm.nih.gov/pubmed/19139281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01182-08
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