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Ctp1(CtIP) and Rad32(Mre11) Nuclease Activity Are Required for Rec12(Spo11) Removal, but Rec12(Spo11) Removal Is Dispensable for Other MRN-Dependent Meiotic Functions
The evolutionarily conserved Mre11/Rad50/Nbs1 (MRN) complex is involved in various aspects of meiosis. Whereas available evidence suggests that the Mre11 nuclease activity might be responsible for Spo11 removal in Saccharomyces cerevisiae, this has not been confirmed experimentally. This study demon...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655602/ https://ncbi.nlm.nih.gov/pubmed/19139281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01182-08 |
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