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Ctp1 and the MRN-Complex Are Required for Endonucleolytic Rec12 Removal with Release of a Single Class of Oligonucleotides in Fission Yeast

DNA double-strand breaks (DSBs) are formed during meiosis by the action of the topoisomerase-like Spo11/Rec12 protein, which remains covalently bound to the 5′ ends of the broken DNA. Spo11/Rec12 removal is required for resection and initiation of strand invasion for DSB repair. It was previously sh...

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Bibliografske podrobnosti
Main Authors: Rothenberg, Maja, Kohli, Jürg, Ludin, Katja
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768786/
https://ncbi.nlm.nih.gov/pubmed/19911044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000722
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