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Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination
Double-strand breaks (DSBs) in DNA are lethal unless repaired. Faithful repair requires processing of the DSB ends and interaction with intact homologous DNA, which can produce genetic recombinants. To determine the role of nucleases in DSB end-processing and joint molecule resolution, we studied re...
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Hoofdauteurs: | , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
National Academy of Sciences
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695049/ https://ncbi.nlm.nih.gov/pubmed/19470480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902793106 |
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