Binding and Internalization of Clostridium botulinum C2 Toxin

Clostridium botulinum C2 toxin is a binary toxin composed of an enzymatic component (C2I) and a binding component (C2II). The activated binding component (C2IIa) forms heptamers, and the oligomer with C2I is taken up by receptor-mediated endocytosis. We investigated the binding and internalization o...

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Main Authors: Nagahama, Masahiro, Hagiyama, Tohko, Kojima, Takashi, Aoyanagi, Kouhei, Takahashi, Chihiro, Oda, Masataka, Sakaguchi, Yoshihiko, Oguma, Keiji, Sakurai, Jun
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772504/
https://ncbi.nlm.nih.gov/pubmed/19720757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00638-09
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