Pharmacological Inhibition of Transforming Growth Factor β Signaling Decreases Infection and Prevents Heart Damage in Acute Chagas' Disease

Chagas' disease induced by Trypanosoma cruzi infection is an important cause of mortality and morbidity affecting the cardiovascular system for which presently available therapies are largely inadequate. We previously reported that transforming growth factor β (TGF-β) is implicated in several r...

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Detalhes bibliográficos
Main Authors: Waghabi, Mariana C., de Souza, Elen M., de Oliveira, Gabriel M., Keramidas, Michelle, Feige, Jean-Jacques, Araújo-Jorge, Tania C., Bailly, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772341/
https://ncbi.nlm.nih.gov/pubmed/19738024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00580-09
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