TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas’ heart disease

TGF-β involvement in Chagas disease cardiomyopathy has been clearly demonstrated. The TGF-β signaling pathway is activated in the cardiac tissue of chronic phase patients and is associated with an increase in extracellular matrix protein expression. The aim of this study was to investigate the effec...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Negl Trop Dis
मुख्य लेखकों: Ferreira, Roberto Rodrigues, Abreu, Rayane da Silva, Vilar-Pereira, Glaucia, Degrave, Wim, Meuser-Batista, Marcelo, Ferreira, Nilma Valéria Caldeira, da Cruz Moreira, Otacílio, da Silva Gomes, Natália Lins, Mello de Souza, Elen, Ramos, Isalira P., Bailly, Sabine, Feige, Jean-Jacques, Lannes-Vieira, Joseli, de Araújo-Jorge, Tania C., Waghabi, Mariana Caldas
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690554/
https://ncbi.nlm.nih.gov/pubmed/31365537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007602
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