Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease

Chronic chagasic cardiomyopathy (CCC) progresses with parasite persistence, fibrosis, and electrical alterations associated with an unbalanced immune response such as high plasma levels of tumor necrosis factor (TNF) and nitric oxide (NO). Presently, the available treatments only mitigate the sympto...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Vilar-Pereira, Glaucia, Resende Pereira, Isabela, de Souza Ruivo, Leonardo Alexandre, Cruz Moreira, Otacilio, da Silva, Andrea Alice, Britto, Constança, Lannes-Vieira, Joseli
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914640/
https://ncbi.nlm.nih.gov/pubmed/27161638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02123-15
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