Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas' Heart Disease

Background. Chagas disease (CD) is characterized by parasite persistence and immunological unbalance favoring systemic inflammatory profile. Chronic chagasic cardiomyopathy, the main manifestation of CD, occurs in a TNF-enriched milieu and frequently progresses to heart failure. Aim of the Study. To...

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Detalhes bibliográficos
Main Authors: Pereira, Isabela Resende, Vilar-Pereira, Glaucia, Silva, Andrea Alice, Moreira, Otacilio Cruz, Britto, Constança, Sarmento, Ellen Diana Marinho, Lannes-Vieira, Joseli
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130030/
https://ncbi.nlm.nih.gov/pubmed/25140115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/798078
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