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Influence of Antidrug Antibodies on Plectasin Efficacy and Pharmacokinetics

Plectasin is a 4.4-kDa antimicrobial peptide with the potential to be a treatment of infections caused by gram-positive bacteria. Since plectasin is a large molecule compared to conventional antibiotics, the development of antidrug antibodies (ADAs) could be anticipated. The immunogenic properties o...

詳細記述

保存先:
書誌詳細
主要な著者: Brinch, Karoline Sidelmann, Frimodt-Møller, Niels, Høiby, Niels, Kristensen, Hans-Henrik
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772336/
https://ncbi.nlm.nih.gov/pubmed/19687247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00440-09
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