High Cerebrospinal Fluid (CSF) Penetration and Potent Bactericidal Activity in CSF of NZ2114, a Novel Plectasin Variant, during Experimental Pneumococcal Meningitis

Plectasin is the first defensin-type antimicrobial peptide isolated from a fungus and has potent activity against gram-positive bacteria. By using an experimental meningitis model, the penetration of plectasin into the cerebrospinal fluid (CSF) of infected and uninfected rabbits and the bactericidal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Østergaard, Christian, Sandvang, Dorthe, Frimodt-Møller, Niels, Kristensen, Hans-Henrik
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663087/
https://ncbi.nlm.nih.gov/pubmed/19188395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01202-08
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