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Influence of Antidrug Antibodies on Plectasin Efficacy and Pharmacokinetics
Plectasin is a 4.4-kDa antimicrobial peptide with the potential to be a treatment of infections caused by gram-positive bacteria. Since plectasin is a large molecule compared to conventional antibiotics, the development of antidrug antibodies (ADAs) could be anticipated. The immunogenic properties o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772336/ https://ncbi.nlm.nih.gov/pubmed/19687247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00440-09 |
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