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Ciprofloxacin Pharmacokinetics/Pharmacodynamics against Susceptible and Low-Level Resistant Escherichia coli Isolates in an Experimental Ascending Urinary Tract Infection Model in Mice

The mouse ascending urinary tract infection model was used to study the pharmacokinetic/pharmacodynamic (PKPD) relationships of the effect of ciprofloxacin in subcutaneous treatment for 3 days with varying doses and dosing intervals against a susceptible Escherichia coli strain (MIC, 0.032 mg/liter)...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jakobsen, Lotte, Lundberg, Carina Vingsbro, Frimodt-Møller, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927838/
https://ncbi.nlm.nih.gov/pubmed/33106267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01804-20
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