Inhibition of Envelope-Mediated CD4(+)-T-Cell Depletion by Human Immunodeficiency Virus Attachment Inhibitors

Human immunodeficiency virus type 1 (HIV-1) envelope (Env) binding induces proapoptotic signals in CD4(+) T cells without a requirement of infection. Defective virus particles, which represent the majority of HIV-1, usually contain a functional Env and therefore represent a potentially significant c...

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Detalhes bibliográficos
Main Authors: Alexander, Louis, Zhang, Sharon, McAuliffe, Brian, Connors, David, Zhou, Nannon, Wang, Tao, Agler, Michele, Kadow, John, Lin, Pin-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772297/
https://ncbi.nlm.nih.gov/pubmed/19721067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00494-09
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