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Glutamate Modulation of Antinociception, but not Tolerance Produced by Morphine Microinjection into the Periaqueductal Gray of the Rat
The periaqueductal gray (PAG) plays an important role in morphine antinociception and tolerance. Co-localization of mu-opioid and NMDA receptors on dendrites in the PAG suggests that glutamate may modulate morphine antinociception. Moreover, the involvement of glutamate in spinally mediated toleranc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772196/ https://ncbi.nlm.nih.gov/pubmed/19664608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.100 |
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