Genetic Association Analysis of the Functional c.714T>G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease

BACKGROUND: Dectin-1 is a pattern recognition receptor (PRR) expressed by myeloid cells that specifically recognizes β-1,3 glucan, a polysaccharide and major component of the fungal cell wall. Upon activation, dectin-1 signaling converges, similar to NOD2, on the adaptor molecule CARD9 which is asso...

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主要な著者: de Vries, Hilbert S., Plantinga, Theo S., van Krieken, J. Han, Stienstra, Rinke, van Bodegraven, Ad A., Festen, Eleonora A. M., Weersma, Rinse K., Crusius, J. Bart A., Linskens, Ronald K., Joosten, Leo A. B., Netea, Mihai G., de Jong, Dirk J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771910/
https://ncbi.nlm.nih.gov/pubmed/19915667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007818
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