Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis

INTRODUCTION: Dectin-1, a pattern recognition receptor expressed by the innate immune system, is known to be a major receptor inducing Th17-type adaptive immune responses that have been demonstrated to mediate autoimmunity. In this study, dectin-1 mRNA and protein expression, as well as the recently...

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Main Authors: Plantinga, Theo S, Fransen, Jaap, Takahashi, Nozomi, Stienstra, Rinke, van Riel, Piet L, van den Berg, Wim B, Netea, Mihai G, Joosten, Leo AB
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875660/
https://ncbi.nlm.nih.gov/pubmed/20158887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2933
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