Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

Mucocutaneous fungal infections are typically found in patients who have no known immune defects. We describe a family in which four women who were affected by either recurrent vulvovaginal candidiasis or onychomycosis had the early-stop-codon mutation Tyr238X in the β-glucan receptor dectin-1. The...

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Main Authors: Ferwerda, Bart, Ferwerda, Gerben, Plantinga, Theo S., Willment, Janet A., van Spriel, Annemiek B., Venselaar, Hanka, Elbers, Clara C., Johnson, Melissa D., Cambi, Alessandra, Huysamen, Cristal, Jacobs, Liesbeth, Jansen, Trees, Verheijen, Karlijn, Masthoff, Laury, Morré, Servaas A., Vriend, Gert, Williams, David L., Perfect, John R., Joosten, Leo A.B., Wijmenga, Cisca, van der Meer, Jos W.M., Adema, Gosse J., Kullberg, Bart Jan, Brown, Gordon D., Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773015/
https://ncbi.nlm.nih.gov/pubmed/19864674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0901053
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