PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes

The programmed death (PD)-1 interacts with its ligand (PDL-1) delivering a negative signal to T cells. During human immunodeficiency virus (HIV)-1 infection PD-1 and PDL-1 expression are increased. Here we show that monocytes and CCR5(+) T cells of HIV-uninfected donors upregulated PDL-1 upon in vit...

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Detaylı Bibliyografya
Asıl Yazarlar: Boasso, Adriano, Hardy, Andrew W., Landay, Alan L., Martinson, Jeffrey L., Anderson, Stephanie A., Dolan, Matthew J., Clerici, Mario, Shearer, Gene M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771672/
https://ncbi.nlm.nih.gov/pubmed/18650129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.05.009
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