PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes

The programmed death (PD)-1 interacts with its ligand (PDL-1) delivering a negative signal to T cells. During human immunodeficiency virus (HIV)-1 infection PD-1 and PDL-1 expression are increased. Here we show that monocytes and CCR5(+) T cells of HIV-uninfected donors upregulated PDL-1 upon in vit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Boasso, Adriano, Hardy, Andrew W., Landay, Alan L., Martinson, Jeffrey L., Anderson, Stephanie A., Dolan, Matthew J., Clerici, Mario, Shearer, Gene M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771672/
https://ncbi.nlm.nih.gov/pubmed/18650129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.05.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados