Protein Kinase D Isoforms Are Expressed In Rat and Mouse Primary Sensory Neurons and Are activated by Agonists Of Protease-Activated Receptor 2

Serine proteases generated during injury and inflammation cleave protease-activated receptor 2 (PAR(2)) on primary sensory neurons to induce neurogenic inflammation and hyperalgesia. Hyperalgesia requires sensitization of transient receptor potential vanilloid (TRPV) ion channels by mechanisms invol...

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Detalhes bibliográficos
Main Authors: Amadesi, Silvia, Grant, Andrew D., Cottrell, Graeme S., Vaksman, Natalya, Poole, Daniel P., Rozengurt, Enrique, Bunnett, Nigel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771637/
https://ncbi.nlm.nih.gov/pubmed/19575452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.22104
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