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Chemokine receptors and other GPCRs

PURPOSE OF REVIEW: Class A G protein-coupled receptors, including the chemokine receptors, CCR5 and CXCR4, share a seven transmembrane-spanning α-helix architecture that accommodates signal propagation from across biological membranes. CXCR4 and CCR5 are utilized as co-receptors during HIV viral ent...

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Bibliographic Details
Main Authors: Lodowski, David T., Palczewski, Krzysztof
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771364/
https://ncbi.nlm.nih.gov/pubmed/19339946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0b013e3283223d8d
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