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The Significance of G Protein-Coupled Receptor Crystallography for Drug Discovery
Crucial as molecular sensors for many vital physiological processes, seven-transmembrane domain G protein-coupled receptors (GPCRs) comprise the largest family of proteins targeted by drug discovery. Together with structures of the prototypical GPCR rhodopsin, solved structures of other liganded GPC...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186081/ https://ncbi.nlm.nih.gov/pubmed/21969326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.110.003350 |
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