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Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme
To try to resolve the loss of stability in the temperature-sensitive mutant of T4 lysozyme, Arg 96 → His, all of the remaining 18 naturally occurring amino acids were substituted at site 96. Also, in response to suggestions that the charged residues Lys85 and Asp89, which are 5–8 Å away, may have im...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771291/ https://ncbi.nlm.nih.gov/pubmed/19384988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.94 |
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