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Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme

To try to resolve the loss of stability in the temperature-sensitive mutant of T4 lysozyme, Arg 96 → His, all of the remaining 18 naturally occurring amino acids were substituted at site 96. Also, in response to suggestions that the charged residues Lys85 and Asp89, which are 5–8 Å away, may have im...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Mooers, Blaine H M, Baase, Walter A, Wray, Jonathan W, Matthews, Brian W
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley Subscription Services, Inc., A Wiley Company 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771291/
https://ncbi.nlm.nih.gov/pubmed/19384988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.94
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