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Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 → His

Mutant R96H is a classic temperature-sensitive mutant of bacteriophage T4 lysozyme. It was in fact the first variant of the protein to be characterized structurally. Subsequently, it has been studied extensively by a variety of experimental and computational techniques, but the reasons for the loss...

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Bibliografische gegevens
Hoofdauteurs: Mooers, Blaine H M, Tronrud, Dale E, Matthews, Brian W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley Subscription Services, Inc., A Wiley Company 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771290/
https://ncbi.nlm.nih.gov/pubmed/19384984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.93
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