Mitochondrial Ubiquitin Ligase MITOL Ubiquitinates Mutant SOD1 and Attenuates Mutant SOD1-induced Reactive Oxygen Species Generation

We have previously identified a novel mitochondrial ubiquitin ligase, MITOL, which is localized in the mitochondrial outer membrane and is involved in the control of mitochondrial dynamics. In this study, we examined whether MITOL eliminates misfolded proteins localized to mitochondria. Mutant super...

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Detalhes bibliográficos
Main Authors: Yonashiro, Ryo, Sugiura, Ayumu, Miyachi, Misako, Fukuda, Toshifumi, Matsushita, Nobuko, Inatome, Ryoko, Ogata, Yoshinobu, Suzuki, Takehiro, Dohmae, Naoshi, Yanagi, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770940/
https://ncbi.nlm.nih.gov/pubmed/19741096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-02-0112
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