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De novo Synthesis of Modified Saxitoxins for Sodium Ion Channel Study
[Image: see text] Access to novel forms of (+)-saxitoxin (STX), a potent and selective inhibitor of voltage-gated Na(+) ion channels, has been made possible through de novo synthesis. Saxitoxin is believed to lodge in the outer mouth of the channel pore, thereby stoppering ion flux. Herein, we demon...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770901/ https://ncbi.nlm.nih.gov/pubmed/19678702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904179f |
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