Fluorescent Saxitoxins for Live Cell Imaging of Single Voltage-Gated Sodium Ion Channels beyond the Optical Diffraction Limit

A desire to better understand the role of voltagegated sodium channels (Na(V)s) in signal conduction and their dysregulation in specific disease states motivates the development of high precision tools for their study. Nature has evolved a collection of small molecule agents, including the shellfish...

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Bibliographic Details
Main Authors: Ondrus, Alison E., Lee, Hsiao-lu D., Iwanaga, Shigeki, Parsons, William H., Andresen, Brian M., Moerner, W.E., Bois, J. Du
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731772/
https://ncbi.nlm.nih.gov/pubmed/22840778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.05.021
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