Yüklüyor......
Conformational inhibition of the HCV IRES RNA
The internal ribosome entry site (IRES), a highly conserved structured element of the hepatitis C virus genomic RNA, is an attractive target for antiviral drugs. Here we show that benzimidazole inhibitors of the HCV replicon act by conformational induction of a widened interhelical angle in the IRES...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770845/ https://ncbi.nlm.nih.gov/pubmed/19767736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.217 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|