Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

The transcription factor SOX9 regulates cartilage extracellular matrix gene expression and is essential for chondrocyte differentiation. We previously showed that activation of p38 MAPK by cycloheximide in human chondrocytes leads to stabilization of SOX9 mRNA (Tew SR and Hardingham TE. J Biol Chem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tew, Simon R., Peffers, Mandy J., McKay, Tristan R., Lowe, Emma T., Khan, Wasim S., Hardingham, Timothy E., Clegg, Peter D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2009
Pynciau:
Receptors and Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770738/
https://ncbi.nlm.nih.gov/pubmed/19657054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00571.2008
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