Transcriptome-Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes

OBJECTIVE: Messenger RNA (mRNA) decay rates control not only gene expression levels, but also responsiveness to altered transcriptional input. We undertook this study to examine transcriptome-wide posttranscriptional regulation in both normal and osteoarthritic (OA) human articular chondrocytes. MET...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Tew, Simon R, McDermott, Benjamin T, Fentem, Rory B, Peffers, Mandy J, Clegg, Peter D
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Osteoarthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233952/
https://ncbi.nlm.nih.gov/pubmed/25155964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38849
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