Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

The transcription factor SOX9 regulates cartilage extracellular matrix gene expression and is essential for chondrocyte differentiation. We previously showed that activation of p38 MAPK by cycloheximide in human chondrocytes leads to stabilization of SOX9 mRNA (Tew SR and Hardingham TE. J Biol Chem...

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Detaylı Bibliyografya
Asıl Yazarlar: Tew, Simon R., Peffers, Mandy J., McKay, Tristan R., Lowe, Emma T., Khan, Wasim S., Hardingham, Timothy E., Clegg, Peter D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2009
Konular:
Receptors and Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770738/
https://ncbi.nlm.nih.gov/pubmed/19657054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00571.2008
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