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Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptide
Competitive capture is a process by which different determinants of an unfolding antigen compete for binding to the same MHC class II molecule. The “winning” determinant is then dominantly displayed. For self antigens, T cells with specificity for dominantly displayed determinants will be subject to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770099/ https://ncbi.nlm.nih.gov/pubmed/18375101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2008.02.004 |
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