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CD8(+) T-cell cross-competition is governed by peptide–MHC class I stability
A major contributing factor to the final magnitude and breadth of CD8(+) T-cell responses to complex antigens is immunodomination, where CD8(+) T cells recognizing their cognate ligand inhibit the proliferation of other CD8(+) T cells engaged with the same APC. In this study, we examined how the hal...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744744/ https://ncbi.nlm.nih.gov/pubmed/22002320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142010 |
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