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Peptide-MHC Class II Complex Stability Governs CD4 T Cell Clonal Selection
The clonal composition of the T cell response can affect its ability to mediate infection control or to induce autoimmunity but the mechanisms regulating the responding TCR repertoire remain poorly defined. Here, we immunized mice with wild-type or mutated peptides displaying varying binding half-li...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975033/ https://ncbi.nlm.nih.gov/pubmed/20007533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902107 |
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