Loading...

(G2)BRinging an E2 to E3

In a recent issue of Molecular Cell, Das et al. (2009) show that the G2BR domain of gp78, a RING-family E3 ubiquitin ligase, binds the E2 Ube2g2 and induces conformational changes within Ube2g2 to allosterically enhance its interaction with cognate E3 RING domains.

Saved in:
Bibliographic Details
Main Authors: Wang, Jing, Schulman, Brenda A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770086/
https://ncbi.nlm.nih.gov/pubmed/19604471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.06.005
Tags: Add Tag
No Tags, Be the first to tag this record!