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Comparative Analysis of In Vitro processivity of HIV-1 Reverse Transcriptases Containing Mutations 65R, 74V, 184V and 65R+74V
While HIV-1 reverse transcriptase (RT) mutations of M to V at position 184 are commonly observed in the clinic, the double mutation of 65R+74V is rarely seen. It has been demonstrated that rapid R→K reversion occurs at RT codon 65 during replication of HIV-1 in human peripheral blood mononuclear cel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769998/ https://ncbi.nlm.nih.gov/pubmed/19555722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.06.002 |
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