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Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones

The DEAD-box proteins CYT-19 in Neurospora crassa and Mss116p in Saccharomyces cerevisiae are broadly acting RNA chaperones that function in mitochondria to stimulate group I and group II intron splicing and activate mRNA translation. Previous studies showed that the S. cerevisiae cytosolic/nuclear...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Campo, Mark Del, Mohr, Sabine, Jiang, Yue, Jia, Huijue, Jankowsky, Eckhard, Lambowitz, Alan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769564/
https://ncbi.nlm.nih.gov/pubmed/19393667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.043
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