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Do DEAD-Box Proteins Promote Group II Intron Splicing Without Unwinding RNA?
The DEAD-box protein Mss116p promotes group II intron splicing in vivo and in vitro. Here we explore two hypotheses for how Mss116p promotes group II intron splicing: by using its RNA unwinding activity to act as an RNA chaperone or by stabilizing RNA folding intermediates. We show that an Mss116p m...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2062517/ https://ncbi.nlm.nih.gov/pubmed/17936712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.07.028 |
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