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ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

DEAD-box proteins, the largest helicase family, catalyze ATP-dependent remodeling of RNA–protein complexes and the unwinding of RNA duplexes. Because DEAD-box proteins hydrolyze ATP in an RNA-dependent fashion, the energy provided by ATP hydrolysis is commonly assumed to drive the energetically unfa...

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Detalhes bibliográficos
Main Authors: Liu, Fei, Putnam, Andrea, Jankowsky, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629341/
https://ncbi.nlm.nih.gov/pubmed/19088201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811115106
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