Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers

Atrial fibrillation is the most common clinical cardiac arrhythmia. It is often initiated by ectopic beats arising from the pulmonary veins and atrium, but the source and mechanism of these beats remains unclear. The melanin synthesis enzyme dopachrome tautomerase (DCT) is involved in intracellular...

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Autors principals: Levin, Mark D., Lu, Min Min, Petrenko, Nataliya B., Hawkins, Brian J., Gupta, Tara H., Lang, Deborah, Buckley, Peter T., Jochems, Jeanine, Liu, Fang, Spurney, Christopher F., Yuan, Li J., Jacobson, Jason T., Brown, Christopher B., Huang, Li, Beermann, Friedrich, Margulies, Kenneth B., Madesh, Muniswamy, Eberwine, James H., Epstein, Jonathan A., Patel, Vickas V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769175/
https://ncbi.nlm.nih.gov/pubmed/19855129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39109
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