Histone-deacetylase Inhibition Reverses Atrial Arrhythmia Inducibility and Fibrosis in Cardiac Hypertrophy Independent of Angiotensin

Atrial fibrosis influences the development of atrial fibrillation (AF), particularly in the setting of structural heart disease where angiotensin-inhibition is partially effective for reducing atrial fibrosis and AF. Histone-deacetylase inhibition reduces cardiac hypertrophy and fibrosis, so we soug...

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Bibliographic Details
Main Authors: Liu, Fang, Levin, Mark D., Petrenko, Nataliya B., Lu, Min Min, Wang, Tao, Yuan, Li Jun, Stout, Andrea L., Epstein, Jonathan A., Patel, Vickas V.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630487/
https://ncbi.nlm.nih.gov/pubmed/18926829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.08.015
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