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Cardiac hypertrophy and histone deacetylase–dependent transcriptional repression mediated by the atypical homeodomain protein Hop

Activation of multiple pathways is associated with cardiac hypertrophy and heart failure. Repression of antihypertrophic pathways has rarely been demonstrated to cause cardiac hypertrophy in vivo. Hop is an unusual homeodomain protein that is expressed by embryonic and postnatal cardiac myocytes. Un...

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Detalhes bibliográficos
Main Authors: Kook, Hyun, Lepore, John J., Gitler, Aaron D., Lu, Min Min, Wing-Man Yung, Wendy, Mackay, Joel, Zhou, Rong, Ferrari, Victor, Gruber, Peter, Epstein, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193673/
https://ncbi.nlm.nih.gov/pubmed/12975471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319137
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