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Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers

Atrial fibrillation is the most common clinical cardiac arrhythmia. It is often initiated by ectopic beats arising from the pulmonary veins and atrium, but the source and mechanism of these beats remains unclear. The melanin synthesis enzyme dopachrome tautomerase (DCT) is involved in intracellular...

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Detalhes bibliográficos
Main Authors: Levin, Mark D., Lu, Min Min, Petrenko, Nataliya B., Hawkins, Brian J., Gupta, Tara H., Lang, Deborah, Buckley, Peter T., Jochems, Jeanine, Liu, Fang, Spurney, Christopher F., Yuan, Li J., Jacobson, Jason T., Brown, Christopher B., Huang, Li, Beermann, Friedrich, Margulies, Kenneth B., Madesh, Muniswamy, Eberwine, James H., Epstein, Jonathan A., Patel, Vickas V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769175/
https://ncbi.nlm.nih.gov/pubmed/19855129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39109
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