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Simultaneous In Vivo Time Course and Dose Response Evaluation for TCDD-Induced Impairment of the LPS-stimulated Primary IgM Response

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent suppressor of humoral immunity but the specific molecular mechanisms responsible for immunosuppression by TCDD are poorly understood. In vivo and in vitro studies of the primary humoral IgM response demonstrated that the B cell is a sensitive ce...

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Bibliografiske detaljer
Main Authors: North, Colin M., Crawford, Robert B., Lu, Haitian, Kaminski, Norbert E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769062/
https://ncbi.nlm.nih.gov/pubmed/19675145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp187
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