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Establishment of an Immunoglobulin M Antibody-Forming Cell Response Model for Characterizing Immunotoxicity in Primary Human B Cells

Rodent models have been extensively utilized to identify putative human immunotoxicants; however, even when immunotoxicity is established, uncertainty remains whether the effects are predictive of human risk. Therefore, the objective of this study was to establish a polyclonal immunoglobulin M (IgM)...

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Autori principali: Lu, Haitian, Crawford, Robert B., North, Colin M., Kaplan, Barbara L. F., Kaminski, Norbert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777081/
https://ncbi.nlm.nih.gov/pubmed/19767444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp224
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