Agonist-Biased Signaling via Proteinase Activated Receptor-2: Differential Activation of Calcium and Mitogen-Activated Protein Kinase Pathways

We evaluated the ability of different trypsin-revealed tethered ligand (TL) sequences of rat proteinase-activated receptor 2 (rPAR(2)) and the corresponding soluble TL-derived agonist peptides to trigger agonist-biased signaling. To do so, we mutated the proteolytically revealed TL sequence of rPAR(...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ramachandran, Rithwik, Mihara, Koichiro, Mathur, Maneesh, Rochdi, Moulay Driss, Bouvier, Michel, DeFea, Kathryn, Hollenberg, Morley D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2009
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769049/
https://ncbi.nlm.nih.gov/pubmed/19605524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.055509
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak