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A yeast killer toxin screen provides insights into A/B toxin entry, trafficking and killing mechanisms

Like Ricin, Shiga, and Cholera toxins, yeast K28 is an A/B toxin that depends on endocytosis and retrograde trafficking for toxicity. Knowledge of the specific proteins, lipids, and mechanisms required for trafficking and killing by these toxins remains incomplete. Since K28 is a model for clinicall...

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Bibliografiska uppgifter
Huvudupphovsmän: Carroll, Susheela Y., Stirling, Peter C., Stimpson, Helen E. M., Gießelmann, Esther, Schmitt, Manfred J., Drubin, David G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768656/
https://ncbi.nlm.nih.gov/pubmed/19853568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.08.006
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